Retrospective Cohort Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2025; 17(8): 105970
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.105970
Retrospective review of anesthesia techniques and postoperative complications in patients with uremia undergoing colorectal cancer surgery
Xue-Jian Zheng, Zhi-Xiong Zhang, Jian Du
Xue-Jian Zheng, Department of Nephrology, Lanxi Traditional Chinese Medicine Hospital, Lanxi 321100, Zhejiang Province, China
Zhi-Xiong Zhang, Department of Anesthesiology, Tianjin Baodi Hospital, Tianjin Medical University Baodi Hospital, Tianjin 301800, China
Jian Du, Department of Anesthesia, Tianjin Beichen District Hospital of Traditional Chinese Medicine, Tianjin 300400, China
Co-first authors: Xue-Jian Zheng and Zhi-Xiong Zhang.
Author contributions: Zheng XJ and Zhang ZX contribute equally to this study as co-first authors; the concept of this study was jointly proposed by Zheng XJ and Du J, who participated in data collection; the initial manuscript was drafted by Zheng XJ; Du J and Zhang ZX contributed to the formal analysis of the data; Zheng XJ guided the research, methodology, and visualization of the manuscript; Zheng XJ, Du J, and Zhang ZX participated in this study and validated it by jointly reviewing and editing the manuscript.
Institutional review board statement: This research has been reviewed and approved by the Ethics Committee of Lanxi Hospital of Traditional Chinese Medicine.
Informed consent statement: This study obtained the informed consent of patients with traditional Chinese medicine in Lanxi City and they signed the relevant informed consent agreement.
Conflict-of-interest statement: The author declares that there is no conflict of interest.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: No available data.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian Du, MD, Associate Chief Physician, Department of Anesthesia, Tianjin Beichen District Hospital of Traditional Chinese Medicine, No. 436 Jingjin Road, Beichen District, Tianjin 300400, China. dujian0871523@126.com
Received: April 25, 2025
Revised: May 21, 2025
Accepted: June 12, 2025
Published online: August 27, 2025
Processing time: 122 Days and 5.2 Hours
Core Tip

Core Tip: This study evaluated the effects of anesthetic techniques and fluid management on postoperative complications in patients with uremia undergoing colorectal cancer surgery. These findings suggest that total intravenous anesthesia and goal-directed fluid therapy significantly reduce complication rates compared with those of inhalational anesthesia and standard fluid therapy. Advanced age, severe uremia, and excessive fluid balance were identified as key risk factors for complications. Optimizing anesthesia and fluid strategies may improve postoperative outcomes and reduce hospital stays in this high-risk population.