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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2025; 17(6): 107086
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.107086
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.107086
Long-term survival with multimodal treatment including conversion surgery for locally advanced esophageal neuroendocrine carcinoma: A case report
Kazuya Okamoto, Kentoku Fujisawa, Yusuke Ogawa, Hayato Shimoyama, Shusuke Haruta, Masaki Ueno, Harushi Udagawa, Department of Gastroenterological Surgery, Toranomon Hospital, Tokyo 105-8470, Tōkyō, Japan
Kei Kono, Yutaka Takazawa, Department of Pathology, Toranomon Hospital, Tokyo 105-8470, Tōkyō, Japan
Author contributions: Okamoto K and Fujisawa K designed the case report and drafted the manuscript; Kono K and Takazawa Y acquired data; Okamoto K, Fujisawa K, Ogawa Y, Shimoyama H, Haruta S, Ueno M, and Udagawa H managed the patient’s care and acquired data; Fujisawa K, Ueno M, and Udagawa H supervised the work; and all authors have reviewed the manuscript and read and approved the final manuscript.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kentoku Fujisawa, MD, Department of Gastroenterological Surgery, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, Tōkyō, Japan. fkentoku@gmail.com
Received: March 18, 2025
Revised: April 4, 2025
Accepted: May 14, 2025
Published online: June 27, 2025
Processing time: 73 Days and 11 Hours
Revised: April 4, 2025
Accepted: May 14, 2025
Published online: June 27, 2025
Processing time: 73 Days and 11 Hours
Core Tip
Core Tip: We used a multimodal treatment approach for locally advanced unresectable esophageal neuroendocrine carcinoma (NEC). Two aspects of this case are noteworthy. First, because NEC was finally diagnosed through postoperative patho