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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. May 27, 2025; 17(5): 105743
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.105743
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.105743
Parenteral nutrition with n-3 polyunsaturated fatty acids on nutrition inflammatory and immune status of gastrointestinal cancer patients: Meta-analysis
Qin-Hu Gan, Xin-Li Gan, Zhi-Qing Jiang, Zhi-Yuan Jian, Department of Gastrointestinal Surgery, Guilin Medical University, Guilin 541001, Guangxi Zhuang Autonomous Region, China
Shu-Qun Li, Department of Hepatobiliary and Pancreatic Surgery, Guilin Medical University, Guilin 541001, Guangxi Zhuang Autonomous Region, China
Author contributions: Gan QH designed the study; Li SQ, Gan XL, and Jiang ZQ analyzed the data; Gan QH and Jian ZY wrote the manuscript; and all authors read and approved the final manuscript.
Supported by the Guangxi Medical and Health Key (Cultivation) Discipline Construction Project; Guilin Scientific Research and Technology Development Program Project, No. 20210227-7-8.
Conflict-of-interest statement: The authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhi-Yuan Jian, Department of Gastrointestinal Surgery, Guilin Medical University, No. 15 Lequn Road, Guilin 541001, Guangxi Zhuang Autonomous Region, China.
Received: February 12, 2025
Revised: March 18, 2025
Accepted: April 8, 2025
Published online: May 27, 2025
Processing time: 100 Days and 0.6 Hours
Revised: March 18, 2025
Accepted: April 8, 2025
Published online: May 27, 2025
Processing time: 100 Days and 0.6 Hours
Core Tip
Core Tip: Nutritional support is an important measure that can improve immunity, reduce the incidence of infectious or non-infectious complications, and enhance the prognosis of patients with malignant tumors. In this study, we conducted a meta-analysis of randomized controlled trials in patients with digestive system malignancies who received n-3 polyunsaturated fatty acids to resolve these ambiguities and evaluate the clinical significance of n-3 polyunsaturated fatty acids in these patients.