Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2023; 15(9): 1995-2002
Published online Sep 27, 2023. doi: 10.4240/wjgs.v15.i9.1995
Clinical significance of serum oxidative stress and serum uric acid levels before surgery for hepatitis B-related liver cancer
Jin-Xia Hou, Yu-Bin Wang, Jing Wu, Guo-sheng Ding, Yang Wu, Lian-Hua Wei, Fang Wang, Zhe-Mei Zhang
Jin-Xia Hou, Yu-Bin Wang, Jing Wu, Guo-sheng Ding, Yang Wu, Lian-Hua Wei, Fang Wang, Zhe-Mei Zhang, Department of Clinical Laboratory, Gansu Provincial Hospital, Gansu Provincial Clinical Research Center for Laboratory Medicine, Lanzhou 730000, Gansu Province, China
Author contributions: Hou JX contributed to manuscript drafting and revision; Wang YB contributed to study design and data analysis; Hou JX and Wang YB contributed equally to this work and are co-first authors; Zhang ZM provided guiding support; Wu J, Ding GS, and Wu Y collected the data; Wei LH and Wang F sorted the data; all authors have read and approved the final manuscript.
Supported by the Gansu Health Industry Research Plan Project, No. GSWSKY-2019-16; and Lanzhou Science and Technology Development Plan Project, No. 2019-ZD-101.
Institutional review board statement: The study was reviewed and approved by the Gansu Provincial Hospital (Approval No. 2023-288).
Informed consent statement: All study participants or their legal guardian provided informed written consent regarding personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: Data for this study can be obtained from the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhe-Mei Zhang, MBBS, Associate Chief Physician, Department of Clinical Laboratory, Gansu Provincial Hospital, Gansu Provincial Clinical Research Center for Laboratory Medicine, No. 204 Donggang West Road, Chengguan District, Lanzhou 730000, Gansu Province, China. zhangzm1122@126.com
Received: June 6, 2023
Peer-review started: June 6, 2023
First decision: June 21, 2023
Revised: June 30, 2023
Accepted: July 26, 2023
Article in press: July 26, 2023
Published online: September 27, 2023
Core Tip

Core Tip: Hepatitis B-related liver cancer is characterized by high morbidity and mortality. Conventional surgery results in a poor prognosis and a high recurrence rate of liver cancer. In this study, we analyzed the clinical data of 110 patients with hepatitis B-related liver cancer who underwent hepatectomy and determined recurrence within three years after surgery. The correlation between preoperative serum oxidative stress level and serum uric acid, and recurrence of hepatitis B-related liver cancer was assessed. These findings provide a breakthrough in prognostic evaluation indicators of liver cancer.