Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2023; 15(8): 1673-1683
Published online Aug 27, 2023. doi: 10.4240/wjgs.v15.i8.1673
Prognostic significance of preoperative lymphocyte to monocyte ratio in patients with signet ring gastric cancer
He-Li Liu, Xiang Feng, Mi-Mi Tang, Hai-Yan Zhou, Huan Peng, Jie Ge, Ting Liu
He-Li Liu, Xiang Feng, Jie Ge, Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
He-Li Liu, The Hunan Provincial Key Laboratory of Precision Diagnosis and Treatment for Gastrointestinal Tumor, The Hunan Provincial Key Laboratory of Precision Diagnosis and Treatment for Gastrointestinal Tumor, Changsha 410008, Hunan Province, China
Mi-Mi Tang, Ting Liu, Institute for Rational and Safe Medication Practices National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
Hai-Yan Zhou, Department of Pathology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
Huan Peng, Clinical Nursing Teaching and Research Section, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
Author contributions: Liu HL, Feng X contributed equally to this work; Liu HL, Feng X and Ge J designed research; Tang MM, Zhou HY and Feng X collected and analyzed clinical data; Liu T, Peng H wrote the paper.
Supported by the Clinical Research Fund of National Geriatric Disease Clinical Medical Research Center, No. 2022LNJ22; Guangdong Yiyang Healthcare Charity Foundation, No. JZ2022014.
Institutional review board statement: The study was reviewed and approved by the Xiangya Hospital, Central South University Institutional Review Board [Approval No. Xykyll-lx-2019030510].
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Ge, MD, Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410008, Hunan Province, China. gejie@csu.edu.cn
Received: May 6, 2023
Peer-review started: May 6, 2023
First decision: May 19, 2023
Revised: May 31, 2023
Accepted: June 21, 2023
Article in press: June 21, 2023
Published online: August 27, 2023
Core Tip

Core Tip: Low preoperative lymphocytes to monocytes levels -predict poor prognosis of patients with signet ring gastric cancer, making it a valuable prognostic factor.