Published online Mar 27, 2021. doi: 10.4240/wjgs.v13.i3.256
Peer-review started: November 3, 2020
First decision: December 20, 2020
Revised: December 23, 2020
Accepted: January 28, 2021
Article in press: January 28, 2021
Published online: March 27, 2021
Core Tip: There have been different reports on mortality of sepsis, but few focus on the prognosis of patients with sepsis after surgery. The purpose of this study was to investigate the prognostic factors of patients with sepsis who were admitted to intensive care unit (ICU) after gastrointestinal surgery. This study retrospectively screened patients who underwent the gastrointestinal tumor surgery at the Peking University Cancer Hospital from January 2015 to December 2019. Among them, 181 patients who were diagnosed with sepsis in ICU were enrolled in our study. In multiple analysis, we found that body mass index ≤ 20 kg/m2, lactic acid after ICU admission, and sequential organ failure assessment (SOFA) score within 24 h after ICU admission might be independent risk predictors of the prognosis of sepsis after gastrointestinal tumor surgery in ICU. Compared with SOFA score, SOFA score combined with body mass index and lactic acid might have higher predictive ability (area under the receiver operating characteristic curve, 0.859; 95% confidence interval, 0.789-0.929).