Retrospective Cohort Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2023; 15(10): 2123-2132
Published online Oct 27, 2023. doi: 10.4240/wjgs.v15.i10.2123
Effect of low anterior resection syndrome on quality of life in colorectal cancer patients: A retrospective observational study
Dong-Ai Jin, Fang-Ping Gu, Tao-Li Meng, Xuan-Xuan Zhang
Dong-Ai Jin, Fang-Ping Gu, Tao-Li Meng, Department of Nursing, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang Province, China
Xuan-Xuan Zhang, Department of Ultrasound, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, Yiwu 322000, Zhejiang Province, China
Author contributions: Jin DA conceptualized and designed the study; Gu FP collected the data; Meng TL analyzed the data; Zhang XX wrote the original draft.
Supported by the Zhejiang Provincial Education Department Project, No. Y202249777 and No. Y201941473.
Institutional review board statement: The study was reviewed and approved by the Sir Run Run Shaw Hospital Medical Ethics Committee (No. 20210607-31).
Informed consent statement: This study was a retrospective study, and the process of data collection, data analysis, and paper writing did not disclose patients' private information, so no informed consent was signed.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for the article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xuan-Xuan Zhang, MD, Chief Doctor, Department of Ultrasound, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, No. 1 Shangcheng Road, Yiwu 322000, Zhejiang Province, China. 8018041@zju.edu.cn
Received: July 4, 2023
Peer-review started: July 4, 2023
First decision: July 19, 2023
Revised: August 1, 2023
Accepted: August 15, 2023
Article in press: August 15, 2023
Published online: October 27, 2023
ARTICLE HIGHLIGHTS
Research background

Low anterior resection syndrome (LARS) is a common complication of anus-preserving surgery for colorectal cancer, which seriously affects the daily life of patients.

Research motivation

In order to reduce the incidence and severity of LARS, while improving the quality of life of patients undergoing colorectal cancer surgery.

Research objectives

The purpose of this study was to investigate the relationship between LARS and patient quality of life in a large cohort of patients and to identify perioperative clinicopathological factors that can predict the occurrence of LARS.

Research methods

This was a longitudinal retrospective cohort study using a hospital-based survey. In this study, the LARS score questionnaire and the European Organization for Research and Treatment of Cancer Core Quality of Life and Colorectal Cancer module questionnaires were completed.

Research results

Multiple independent risk factors for LARS were identified in the study. The accuracy of the LARS prediction model established was 0.808.

Research conclusions

The LARS prediction model in this study can implement perioperative precision nursing and improve the quality of life of LARS patients.

Research perspectives

The LARS prediction model would enable the implementation of perioperative precision nursing interventions to improve patient quality of life.