Published online Sep 27, 2021. doi: 10.4240/wjgs.v13.i9.988
Peer-review started: March 22, 2021
First decision: May 13, 2021
Revised: May 17, 2021
Accepted: August 10, 2021
Article in press: August 10, 2021
Published online: September 27, 2021
As a potentially life-threatening complication of simultaneous pancreas and kidney transplantation (SPKT), enteric anastomotic (EA) bleeding frequently results in surgical relaparotomy and graft loss; therefore, it is essential to decrease the incidence of EA bleeding.
An effort was made for submucosal hemostasis during enteric anastomosis in SPKT with a lower EA bleeding rate.
To investigate the advantages and disadvantages of suture ligation (SL) for submucosal hemostasis during enteric anastomosis on early EA bleeding and anastomotic leakage in SPKT.
We compared the outcomes of 134 patients classified into SL (n = 44) and no SL (NSL) groups (n = 90).
During the first postoperative week, the EA bleeding rate in the SL group was lower than that in the NSL group during the first postoperative week. No relationship was found between EA bleeding and donor age, mean pancreatic cold ischemia time, platelet count, prothrombin time international normalized rate, activated partial thromboplastin time, and thrombin time. No significant difference was noted between the two groups in terms of the anastomotic leakage rate, patient survival curve, pancreas graft survival curve, or kidney graft survival curve.
Compared with no SL, SL for submucosal hemostasis during enteric anastomosis in SPKT can decrease the EA bleeding rate and do not increase the anastomotic leakage rate.
Further clinical randomized controlled studies with a large sample size are needed to confirm the effect of plication techniques on submucosal hemostasis during enteric anastomosis in SPKT in the future.