Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2025; 17(6): 106264
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.106264
Impact of enhanced bowel preparation on complications and prognosis following colonoscopic polypectomy
Yan-Ping Ma, Xue-Yong Zheng, Xin-Feng Shen, Yi-Ting Ling, Mei-Ping Qian, Min-Jun Ni
Yan-Ping Ma, Xin-Feng Shen, Mei-Ping Qian, Min-Jun Ni, Endoscopy Center, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China
Xue-Yong Zheng, Yi-Ting Ling, Department of General Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China
Co-first authors: Yan-Ping Ma and Xue-Yong Zheng.
Author contributions: Ma YP and Zheng XY designed the research study; Ma YP, Zheng XY and Shen XF performed the research; Ling YT, Qian MP and Ni MJ contributed new reagents and analytic tools; Shen XF, Ma YP and Zheng XY analyzed the data and wrote the manuscript. All authors have read and approved the final manuscript. Ma YP and Zheng XY contributed equally to this study.
Supported by Jiaxing Science and Technology Projects, No. 2023AD31041.
Institutional review board statement: This study was reviewed and approved by the Medical Ethics Committee of The Second Affiliated Hospital of Jiaxing University (No. Jinxing Second Hospital Ethics Review 2023JX057-01).
Informed consent statement: Informed consent was waived by the Ethics Committee of The Second Affiliated Hospital of Jiaxing University due to the retrospective nature of the study and the use of anonymized patient data.
Conflict-of-interest statement: Raw data can be obtained by contacting the corresponding author.
Data sharing statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xin-Feng Shen, Endoscopy Center, The Second Affiliated Hospital of Jiaxing University, No. 1518 Huancheng North Road, Nanhu District, Jiaxing 314000, Zhejiang Province, China. sxfsxf5036@163.com
Received: March 7, 2025
Revised: April 4, 2025
Accepted: May 9, 2025
Published online: June 27, 2025
Processing time: 84 Days and 3.2 Hours
Abstract
BACKGROUND

Colonoscopic polypectomy is a crucial procedure for the prevention and treatment of colorectal cancer, with its success and safety largely dependent on the quality of bowel preparation. Currently, polyethylene glycol electrolyte solution remains the standard method for bowel preparation, but its use may cause patient discomfort and incomplete cleansing.

AIM

To evaluate impact of enhanced and conventional bowel preparation protocols on the outcomes of colonoscopic polypectomy.

METHODS

This retrospective cohort study collected data from 130 patients who underwent colonoscopic polypectomy between March 2023 and June 2024. Patients were divided into the conventional bowel preparation group (n = 65) and enhanced bowel preparation group (n = 65). Primary outcome measures included Boston Bowel Preparation Scale (BBPS) scores, procedure-related parameters, complication rates, and prognosis. Statistical analysis was performed using SPSS version 25.0, with P < 0.05 indicating statistical significance.

RESULTS

The enhanced group demonstrated significant advantages over the conventional group, with higher BBPS total scores (4.2 ± 0.7 vs 3.1 ± 0.8, P < 0.001), higher one-time complete resection rates (95.4% vs 83.1%, P = 0.01), shorter operative times (23.1 ± 4.8 vs 25.4 ± 5.2 min, P = 0.03), and lesser intraoperative blood loss (18.2 ± 4.5 vs 20.3 ± 5.1 mL, P = 0.04). Total complication rates were significantly lower (5.9% vs 16.9%, P = 0.05), particularly for bleeding (1.5% vs 16.9%, P = 0.01) and infection (1.5% vs 7.7%, P = 0.04). The enhanced group also showed lower 6-month recurrence rates (3.1% vs 10.8%, P = 0.05) and higher patient satisfaction (87.7% vs 76.9%, P = 0.04) than did the conventional group.

CONCLUSION

The enhanced bowel preparation protocol demonstrates significant advantages, particularly in improving surgical outcomes, reducing complications, and increasing patient satisfaction, underscoring its importance of its application during colonoscopic polypectomy.

Keywords: Colonoscopic polypectomy; Bowel preparation; Complications; Patient satisfaction; Prognosis

Core Tip: This study evaluates the impact of enhanced vs conventional bowel preparation protocols on colonoscopic polypectomy outcomes, highlighting the superior efficacy of the enhanced approach. The findings reveal significant improvements in bowel preparation quality, one-time complete resection rates, operative efficiency, and patient satisfaction, alongside reduced complication rates and lower 6-month recurrence rates. These results underscore the clinical importance of adopting enhanced bowel preparation protocols to optimize surgical outcomes and enhance patient care in colonoscopic polypectomy.