Comparison of three diagnostic imaging modalities for use in diabetic inferior arterial lesions

Table 1 Comparison of general information

Characteristics	DM group (n = 116)	Control group (n = 60)	χ2/t	P value
Age (year)	53.62 ± 3.37	53.78 ± 3.09	0.307	0.759
Gender			2.158	0.142
Male	54	21
Female	62	39
Hyperlipidemia	41	19	0.238	0.626
Hypertension	54	23	1.085	0.297
Coronary heart disease	38	16	0.690	0.406
Course of DM (year)	7.35 ± 0.41
Fasting blood glucose (mmol/L)	8.17 ± 1.04	4.36 ± 0.59	26.253	< 0.0001
2-h postprandial blood glucose (mmol/L)	12.87 ± 1.48	7.01 ± 0.63	29.296	< 0.0001
Glycosylated hemoglobin (%)	9.81 ± 0.67	5.41 ± 0.52	44.399	< 0.0001

DM: Diabetes mellitus.

Table 2 Digital subtraction angiography diagnosis results of patients

Arterial branch classification	Mild stenosis	Moderate stenosis	Severe stenosis or occlusion	Total
Grade 1	78	51	23	152
Grade 2	50	53	49	152
Grade 3	85	47	20	152

Table 3 Diagnostic value of doppler ultrasonography for different arterial branches in diabetic lower extremity arterial disease

Degree of stenosis	Arterial branch classification	DUS diagnosis	DSA diagnosis		Kappa	Sensitivity (%)	Specificity (%)	Accuracy (%)
			Moderate/severe	Non-moderate/non-severe
Moderate stenosis	Grade 1	Moderate	44	8	0.780	86.3	92.1	90.1
		Non-moderate	7	93
	Grade 2	Moderate	45	9	0.755	84.9	90.9	88.8
		Non-moderate	8	90
	Grade 3	Moderate	43	9	0.806	91.5	91.4	91.4
		Non-moderate	4	96
Severe stenosis or occlusion	Grade 1	Severe	18	23	0.484	82.6	82.2	82.2
		Non-severe	5	106
	Grade 2	Severe	39	10	0.699	79.6	90.3	86.8
		Non-severe	10	93
	Grade 3	Severe	14	18	0.449	70.0	86.4	84.2
		Non-severe	6	114

DUS: Doppler ultrasonography; DSA: Digital subtraction angiography.

Table 4 Value of contrast-enhanced magnetic resonance angiography in diagnosing diabetic lower extremity arterial disease of arterial branches of different grades

Degree of stenosis	Arterial branch classification	CE-MRA diagnosis	DSA diagnosis		Kappa	Sensitivity (%)	Specificity (%)	Accuracy (%)
			Moderate/severe	Non-moderate/non-severe
Moderate stenosis	Grade 1	Moderate	46	10	0.784	90.2	90.1	90.1
		Non-moderate	5	91
	Grade 2	Moderate	48	8	0.814	90.6	91.9	91.4
		Non-moderate	5	91
	Grade 3	Moderate	44	8	0.835	93.6	92.4	92.8
		Non-moderate	3	97
Severe stenosis or occlusion	Grade 1	Severe	19	9	0.694	82.6	93.0	91.4
		Non-severe	4	120
	Grade 2	Severe	42	10	0.748	85.7	90.3	88.8
		Non-severe	7	93
	Grade 3	Severe	16	12	0.606	80.0	90.9	89.5
		Non-severe	4	120

CE-MRA: Contrast-enhanced magnetic resonance angiography; DSA: Digital subtraction angiography.

Table 5 Diagnostic value of computerized tomography angiography for different arterial branches in diabetic lower-extremity arterial disease

Degree of stenosis	Arterial branch classification	CTA diagnosis	DSA diagnosis		Kappa	Sensitivity (%)	Specificity (%)	Accuracy (%)
			Moderate/sever	Non-moderate/non-severe
Moderate stenosis	Grade 1	Moderate	51	7	0.900	100.0	93.1	95.4
		Non-moderate	0	94
	Grade 2	Moderate	50	7	0.858	94.3	92.9	93.4
		Non-moderate	3	92
	Grade 3	Moderate	44	5	0.878	93.6	95.2	94.7
		Non-moderate	3	100
Severe stenosis or occlusion	Grade 1	Severe	23	5	0.882	100.0	96.1	96.7
		Non-severe	0	124
	Grade 2	Severe	45	8	0.823	91.8	92.2	92.1
		Non-severe	4	95
	Grade 3	Severe	17	6	0.756	85.0	95.5	94.1
		Non-severe	3	126

CTA: Computerized tomography angiography; DSA: Digital subtraction angiography.