Retrospective Study
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jul 15, 2018; 9(7): 132-137
Published online Jul 15, 2018. doi: 10.4239/wjd.v9.i7.132
New-onset diabetes after kidney transplantation: Incidence and associated factors
Vânia Gomes, Florbela Ferreira, José Guerra, Maria João Bugalho
Vânia Gomes, Florbela Ferreira, Maria João Bugalho, Endocrinology, Diabetes and Metabolism Department, Santa Maria Hospital, Lisbon 1649-035, Portugal
José Guerra, Nephrology and Kidney Transplantation Department, Santa Maria Hospital, Lisbon 1649-035, Portugal
Author contributions: Gomes V wrote the manuscript, collected the data and performed the data analysis; Guerra J collected the data; Guerra J, Ferreira F and Bugalho MJ reviewed the manuscript for important intellectual content; all authors participated in designing the study.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Santa Maria Hospital (No. 406/17).
Informed consent statement: Informed consent was not required for study participation or data publication because the clinical data were collected from an institutional database and had been anonymized before analysis.
Conflict-of-interest statement: All authors declare no conflicts-of-interest in relation to this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Vânia Gomes, MD, Doctor, Endocrinology, Diabetes and Metabolism Department, Santa Maria Hospital, Avenida Professor Egas Moniz, Lisbon 1649-035, Portugal. vania.rodrigues.gomes@gmail.com
Telephone: +351-912-993251
Received: March 22, 2018
Peer-review started: March 23, 2018
First decision: May 8, 2018
Revised: May 24, 2018
Accepted: June 13, 2018
Article in press: June 13, 2018
Published online: July 15, 2018
Core Tip

Core tip: New-onset diabetes mellitus after transplantation (NODAT) is a major complication of kidney transplant. The aim of this study was to evaluate the incidence and associated factors of NODAT among kidney transplant recipients in a single center. A total of 125 patients transplanted at Santa Maria Hospital (Lisbon, Portugal) were assessed, and NODAT was identified in 27.2%. The median time to diagnosis was 3.68 ± 5.7 mo after transplantation and most patients (76.5%) developed NODAT in the first 3 mo posttransplant. Higher pretransplant fasting plasma glucose level and pretransplant impaired fasting glucose were predictive risk factors for NODAT development.