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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Mar 25, 2016; 7(6): 134-141
Published online Mar 25, 2016. doi: 10.4239/wjd.v7.i6.134
Published online Mar 25, 2016. doi: 10.4239/wjd.v7.i6.134
Infantile onset diabetes mellitus in developing countries - India
Poovazhagi Varadarajan, Department of Pediatrics, Chengalpattu Medical College and Hospital, Chengalpattu, Tamil Nadu 603001, India
Author contributions: Varadarajan P was the only author for this review.
Conflict-of-interest statement: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Poovazhagi Varadarajan, Professor of Pediatrics, Department of Pediatrics, Chengalpattu Medical College and Hospital, 8/11 Manjolai Street, Kalaimagal Nagar, Chengalpattu, Tamil Nadu 603001, India. poomuthu@yahoo.com
Telephone: +91-44-22251515
Received: October 18, 2015
Peer-review started: October 20, 2015
First decision: November 11, 2015
Revised: December 14, 2015
Accepted: January 21, 2016
Article in press: January 22, 2016
Published online: March 25, 2016
Peer-review started: October 20, 2015
First decision: November 11, 2015
Revised: December 14, 2015
Accepted: January 21, 2016
Article in press: January 22, 2016
Published online: March 25, 2016
Core Tip
Core tip: The clinical presentation of infantile onset diabetes mellitus (IODM) as syndromic and non-syndromic forms from South India is discussed in this article. Associated co-morbid states, mortality pattern, difficulty in the management and need for genetic evaluation among this group of infants are also discussed. Identification of this form of monogenic diabetes by clinical evaluation and appropriate genetic evaluation to identify the subtypes helps in the management of these infants to improve the overall morbidity and mortality. Reported mortality in IODM is high from South India.