Systematic Reviews
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Dec 15, 2016; 7(20): 627-630
Published online Dec 15, 2016. doi: 10.4239/wjd.v7.i20.627
Intermittent energy restriction in type 2 diabetes: A short discussion of medication management
Sharayah Carter, Peter M Clifton, Jennifer B Keogh
Sharayah Carter, Peter M Clifton, Jennifer B Keogh, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5000, Australia
Author contributions: The short review was written by Carter S; Clifton PM and Keogh JB edited the paper; all authors have read and approved the paper.
Conflict-of-interest statement: All the authors declare that they have no competing interests. There was no funding.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Peter M Clifton, Professor of Nutrition, School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA 5000, Australia. peter.clifton@unisa.edu.au
Telephone: +61-403-197998
Received: July 1, 2016
Peer-review started: July 6, 2016
First decision: September 5, 2016
Revised: September 16, 2016
Accepted: October 17, 2016
Article in press: October 18, 2016
Published online: December 15, 2016
Core Tip

Core tip: Use of the popular 5:2 intermittent energy restriction diet in people with type 2 diabetes requires careful manipulation of oral hypoglycemic agents and insulin to prevent poor blood glucose control. This short review fills a very important gap in the literature, reviewing necessary medication changes required in severe energy restriction and outlining how these changes may apply during the 5:2 diet by sharing our experiences from our recent 5:2 pilot trial.