Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Aug 10, 2015; 6(9): 1097-1107
Published online Aug 10, 2015. doi: 10.4239/wjd.v6.i9.1097
Published online Aug 10, 2015. doi: 10.4239/wjd.v6.i9.1097
Aloesin as a medical food ingredient for systemic oxidative stress of diabetes
Mesfin Yimam, Lidia Brownell, Qi Jia, Unigen, Inc., Seattle, WA 98121, United States
Author contributions: All authors contributed to this manuscript.
Conflict-of-interest statement: Mesfin Yimam, Lidia Brownell and Qi Jia are currently Unigen employees and therefore, have competing financial interests. In addition, Qi Jia is the co-inventor of US issued patent entitled 7-Hydroxy Chromones as Potent Anti-oxidant.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Mesfin Yimam, DVM, MS, Unigen, Inc., 3005 1st Ave, Seattle, WA 98121, United States. myimam@unigen.net
Telephone: +1-360-4868200 Fax: +1-360-4139135
Received: April 22, 2015
Peer-review started: April 22, 2015
First decision: May 13, 2015
Revised: July 1, 2015
Accepted: July 24, 2015
Article in press: July 27, 2015
Published online: August 10, 2015
Peer-review started: April 22, 2015
First decision: May 13, 2015
Revised: July 1, 2015
Accepted: July 24, 2015
Article in press: July 27, 2015
Published online: August 10, 2015
Core Tip
Core tip: Diabetes has become epidemic in industrialized countries; Diabetes is a chronic disease with no cure; Oxidative stress plays a pivotal role in diabetes complication; Aloesin and aloe polysaccharides have strong free radical scavenging activities; Aloesin formulated with aloe polysaccharides has shown merits in diabetes management in human clinical trials; Aloesin formulated with aloe polysaccharides could have potentials in combating diabetes associated oxidative stress or to be used as an adjunct to pharmaceutical drugs.