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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Feb 15, 2015; 6(1): 54-66
Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.54
Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.54
Pathogenesis of diabetic cerebral vascular disease complication
Ren-Shi Xu, Department of Neurology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Author contributions: Xu RS performed the literature review, integrated key scientific concepts and wrote the paper.
Supported by National Nature Science foundation of China (NSFC), No. 30560042, No. 81160161 and No. 81360198; by the Education Department of Jiangxi province (EDJX), No. GJJ10303.
Conflict-of-interest: The author declares that he has no competing interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ren-Shi Xu, MD, PhD, Department of Neurology, the First Affiliated Hospital of Nanchang University, No. 17 of Yongwaizheng St., Nanchang 330006, Jiangxi Province, China. xurenshi@yahoo.com
Telephone: +86-791-88603798
Received: June 30, 2014
Peer-review started: July 2, 2014
First decision: September 18, 2014
Revised: November 20, 2014
Accepted: December 3, 2014
Article in press: December 10, 2014
Published online: February 15, 2015
Peer-review started: July 2, 2014
First decision: September 18, 2014
Revised: November 20, 2014
Accepted: December 3, 2014
Article in press: December 10, 2014
Published online: February 15, 2015
Core Tip
Core tip: A better understanding pathogenesis of diabetic cerebral vascular disease (CVD) could provide the basis for developing novel therapeutic strategies against diabetic CVD complication. Our article highlights the pathogenesis as some promising options to prevent CVD complications in diabetes, including metabolic and vascular changes and main pathways are involved in diabetic CVD complication.