Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.17
Peer-review started: August 28, 2014
First decision: September 19, 2014
Revised: September 26, 2014
Accepted: December 1, 2014
Article in press: December 1, 2014
Published online: February 15, 2015
Core tip: Hemoglobin A1c is the gold standard to assess glycemic control and a surrogate for diabetes-associated complications. Self-monitoring of blood glucose complements daily diabetes management but is insufficient in providing complete information on short-term changes in glucose levels induced by effects of food or antidiabetic medication. Key metrics beyond HbA1c are needed for glycemic control on a day-to-day basis as well as more advanced monitoring methods. Herein, we will review advantages and limitations of different metrics for glycemic control as well as possibilities for characterization of glucose dynamics with the special focus on glycemic variability and continuous glucose monitoring.