Randomized Controlled Trial
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World J Diabetes. Dec 15, 2014; 5(6): 962-968
Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.962
Flavonoid-rich beverage effects on lipid profile and blood pressure in diabetic patients
Reza Amani, Sara Moazen, Hajieh Shahbazian, Kambiz Ahmadi, Mohammad Taha Jalali
Reza Amani, Sara Moazen, Department of Nutrition, School of Paramedicine, Diabetes Research Center, Jundishapour University of Medical Sciences, Ahvaz 61357-15794, Iran
Hajieh Shahbazian, Diabetes Research Center, Jundishapour University of Medical Sciences, Ahvaz 61357-15794, Iran
Kambiz Ahmadi, Department of Medical Statistics, School of Public Health, Jundishapour University of Medical Sciences, Ahvaz 61357-15794, Iran
Mohammad Taha Jalali, Department of Laboratory Sciences, School of Paramedicine, Jundishapour University of Medical Sciences, Ahvaz 61357-15794, Iran
Author contributions: Moazen S collected the data, drafted the manuscript, and contributed to intellectual discussions; Amani R supervised the study, reviewed/edited the manuscript, and contributed to intellectual discussions; Shahbazian H helped with management of the diabetic patients; Ahmadi K performed statistical analysis; Jalali MT helped with laboratory interpretation.
Supported by A grant from the Vice-Chancellor of the Research and Diabetes Research Center of Jundishapour University of Medical Science, No. ETH-393
Correspondence to: Sara Moazen, MSc, Department of Nutrition, School of Paramedicine, Diabetes Research Center, Jundishapour University of Medical Sciences, Golestan Blvd, Ahvaz 61357-15794, Iran. sm.yaghmur@gmail.com
Telephone: +98-61-13738319 Fax: +98-61-13738330
Received: June 16, 2014
Revised: July 30, 2014
Accepted: September 11, 2014
Published online: December 15, 2014
Core Tip

Core tip: Cardiovascular complications are the main cause of mortality in diabetes patients. Considering the role of flavonoids in modulating the latter complications, this study was designed to test the favorable impact of freeze-dried strawberry (FDS) drink, a flavonoid-rich beverage, on the metabolic profile of diabetes patients in a randomized, double-blind, placebo control trial. Lipid profile and blood pressure were improved in patients who consumed the FDS drink for 6 wk. Effects of the latter intervention on other atherosclerotic biomarkers have been discussed separately in Ann Nutr Metab 2013; 63: 256-264. This paper describes the further analysis of other metabolic biomarkers.