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World J Diabetes. Dec 15, 2014; 5(6): 924-931
Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.924
Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.924
Effect of periodontal treatment on adipokines in type 2 diabetes
Hiroshi Ogawa, Teerasak Damrongrungruang, Sayaka Hori, Kaname Nouno, Kumiko Minagawa, Misuzu Sato, Hideo Miyazaki, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan
Teerasak Damrongrungruang, Department of Oral Diagnosis, Khon Kaen University, Muang, Khon Kaen 40002, Thailand
Author contributions: Damrongrungruang T, Hori S, Nouno K, Minagawa K and Sato M searched the articles; Damrongrungruang T and Nouno K analysed data; Hori S drew the figures; Ogawa H, Damrongrungruang T and Miyazaki H wrote the paper.
Correspondence to: Hiroshi Ogawa, DDS, PhD, Associate Professor, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Science, Niigata University, 2-5274, Gakkocho-Dori, Chuo-Ku, Niigata 951-8514, Japan. ogahpre@dent.niigata-u.ac.jp
Telephone: +81-25-2272858 Fax: +81-25-2270807
Received: August 26, 2014
Revised: September 29, 2014
Accepted: November 7, 2014
Published online: December 15, 2014
Revised: September 29, 2014
Accepted: November 7, 2014
Published online: December 15, 2014
Core Tip
Core tip: Several adipokines could serves as the monitoring molecules that reflect overall and oral disease conditions include periodontitis. Because they are rapidly change upon the change in body and oral conditions. The treatment response and disease activity progression may also predicted using these kinds of molecules. Moreover, the method to collect and analyse adipokines is relatively simple because they can be detected in gingival crevicular fluid and analysed using general enzyme-linked immunosorbent assay technology. Collectively, clinicians include medical doctors and periodontists should take the concern regarding adipokines into their routine periodontal treatment plan and management.