Prospective Study
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World J Diabetes. Oct 15, 2014; 5(5): 724-729
Published online Oct 15, 2014. doi: 10.4239/wjd.v5.i5.724
Perfluorocarbon in vitreoretinal surgery and preoperative bevacizumab in diabetic tractional retinal detachment
J Fernando Arevalo, Martin A Serrano, Juan D Arias
J Fernando Arevalo, From the Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States
J Fernando Arevalo, the Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh 11462, Saudi Arabia
J Fernando Arevalo, Division of Ophthalmology, Faculty of Medicine and Health Sciences, University of Stellenbosch, Stellenbosch 7600, South Africa
Martin A Serrano, Juan D Arias, the Retina and Vitreous Service, Clinica Oftalmologica Centro Caracas, Caracas 1010, Venezuela
Author contributions: Arevalo JF performed all surgeries, designed the study and wrote the manuscript; and Serrano MA and Arias JD assisted during all surgeries and collected data; Serrano MA and Arias JD were also involved in editing the manuscript.
Supported by The Arevalo-Coutinho Foundation for Research in Ophthalmology, Caracas, Venezuela
Correspondence to: J Fernando Arevalo, MD, FACS, Chief of the Vitreoretinal Division, King Khaled Eye Specialist Hospital, Al-Oruba Street, PO Box 7191, Riyadh 11462, Saudi Arabia. arevalojf@jhmi.edu
Telephone: +966-11-48212343860 Fax: +966-1-48212343727
Received: November 28, 2013
Revised: June 26, 2014
Accepted: July 15, 2014
Published online: October 15, 2014
Core Tip

Core tip: En bloc perfluorodissection and preoperative intravitreal bevacizumab use for small-gauge vitrectomy in patients with proliferative diabetic retinopathy and tractional retinal detachment are very useful, the combination reduces complications and operative time. En bloc perfluorodissection and preoperative intravitreal bevacizumab use seems to have many advantages including that the retina remains stable during vitrectomy, better visibility of the ocular structures in the vitreous cavity, immediate reattachment of the retina, bleeding control, subretinal fluid reabsorbsion and drainage, bleeding sites’ tamponade, and easier dissection of epiretinal tissues.