Prognostic value of endothelial dysfunction in type 1 diabetes mellitus

doi:10.4239/wjd.v5.i5.601

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Oct 15, 2014 (publication date) through Apr 19, 2024

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World Journal of Diabetes

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1948-9358

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World J Diabetes. Oct 15, 2014; 5(5): 601-605
Published online Oct 15, 2014. doi: 10.4239/wjd.v5.i5.601

Prognostic value of endothelial dysfunction in type 1 diabetes mellitus

Ana Marice Ladeia, Raphael Ribeiro Sampaio, Maiara Costa Hita, Luis F Adan

Ana Marice Ladeia, Raphael Ribeiro Sampaio, Maiara Costa Hita, Bahiana School of Medicine and Public Health, Bahia Foundation for the Development of Sciences, FBDC, Salvador, Bahia 40.285-001, Brazil

Luis F Adan, Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Bahia 40.026-010, Brazil

Author contributions: Ladeia AM conceived the manuscript, acquired and interpreted the data and drafted the article; Sampaio RR and Hita MC participated in the acquisition and interpretation of data; Adan LF made the final critical review of the manuscript.

Correspondence to: Ana Marice Ladeia, MD, PhD, Bahiana School of Medicine and Public Health, Bahia Foundation for the Development of Sciences, FBDC, Avenida D. João VI 275, Salvador, Bahia 40.285-001, Brazil. anamarice@bahiana.edu.br

Telephone: +55-71-32768265

Received: June 3, 2014
Revised: June 30, 2014
Accepted: July 18, 2014
Published online: October 15, 2014

Core Tip

Core tip: This review is divided into two parts: first we discuss aspects related to the pathogenesis of endothelial dysfunction in type 1 diabetes mellitus. In the second, are pointed out and critically discussed the scientific evidence about the important role of endothelial dysfunction, independent of the method used for its diagnosis, as an early marker of cardiovascular and renal complications in this population.