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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Aug 15, 2014; 5(4): 536-545
Published online Aug 15, 2014. doi: 10.4239/wjd.v5.i4.536
Published online Aug 15, 2014. doi: 10.4239/wjd.v5.i4.536
Novel treatment approaches in hypertensive type 2 diabetic patients
Yaniel Castro Torres, Facultad de Medicina, Universidad de Ciencias Médicas Dr. Serafín Ruiz de Zárate Ruiz, Santa Clara 50100, Villa Clara, Cuba
Richard E Katholi, Southern Illinois University School of Medicine and Prairie Cardiovascular Consultants, Springfield, IL 62701, United States
Author contributions: Castro Torres Y and Katholi RE were both involved in the design of the manuscript; both wrote major sections and both contributed to multiple revisions.
Correspondence to: Richard E Katholi, MD, Prairie Cardiovascular Consultants, Southern Illinois University School of Medicine and Prairie Cardiovascular Consultants, 619 E. Mason St., Ste.4P57, Springfield, IL 62701, United States. rkatholi@prairieheart.com
Telephone: +1-217-7880706 Fax: +1-217-7576502
Received: March 14, 2014
Revised: May 6, 2014
Accepted: June 10, 2014
Published online: August 15, 2014
Revised: May 6, 2014
Accepted: June 10, 2014
Published online: August 15, 2014
Core Tip
Core tip: Type 2 diabetes mellitus and hypertension are two common conditions worldwide which increase the risk of cardiovascular disease with resulting disabilities and mortality. Carvedilol and renal denervation are two promising therapies to decrease insulin resistance and lower blood pressure by attenuating sympathetic nervous system activity. This review examines the clinical reports of these novel approaches.