Published online Aug 15, 2014. doi: 10.4239/wjd.v5.i4.536
Revised: May 6, 2014
Accepted: June 10, 2014
Published online: August 15, 2014
Core tip: Type 2 diabetes mellitus and hypertension are two common conditions worldwide which increase the risk of cardiovascular disease with resulting disabilities and mortality. Carvedilol and renal denervation are two promising therapies to decrease insulin resistance and lower blood pressure by attenuating sympathetic nervous system activity. This review examines the clinical reports of these novel approaches.