Antidiabetic treatment, stroke severity and outcome

doi:10.4239/wjd.v5.i2.84

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Apr 15, 2014; 5(2): 84-88
Published online Apr 15, 2014. doi: 10.4239/wjd.v5.i2.84

Antidiabetic treatment, stroke severity and outcome

Dimitra Magkou, Konstantinos Tziomalos

Dimitra Magkou, Konstantinos Tziomalos, First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki 54636, Greece

Author contributions: Magkou D drafted the paper; Tziomalos K revised the draft critically for important intellectual content.

Correspondence to: Konstantinos Tziomalos, MD, PhD, First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, 1 St. Kyriakidi, Thessaloniki 54636, Greece. ktziomalos@yahoo.com

Telephone: +30-2310-994621 Fax: +30-2310-994773

Received: September 4, 2013
Revised: November 2, 2013
Accepted: January 6, 2014
Published online: April 15, 2014

Core Tip

Core tip: A recent study showed reduced stroke size following pretreatment with linagliptin, a dipeptidyl peptidase-4 (DDP-4) inhibitor, compared with glimepiride, in both diabetic and non-diabetic mice. It remains to be shown whether these neuroprotective actions of DPP-4 inhibitors will also be observed in humans.