Role of P2X7 receptors in the development of diabetic retinopathy

doi:10.4239/wjd.v5.i2.141

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Apr 15, 2014 (publication date) through Apr 24, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Diabetes. Apr 15, 2014; 5(2): 141-145
Published online Apr 15, 2014. doi: 10.4239/wjd.v5.i2.141

Role of P2X₇ receptors in the development of diabetic retinopathy

Tetsuya Sugiyama

Tetsuya Sugiyama, Nakano Eye Clinic of Kyoto Medical Co-operative, Kyoto 604-8404, Japan

Author contributions: Sugiyama T designed and wrote this “Topic Highlight”.

Correspondence to: Tetsuya Sugiyama, MD, PhD, Director, Nakano Eye Clinic of Kyoto Medical Co-operative, 2, Juraku-mawari-higashimachi, Nakagyo-ku, Kyoto 604-8404, Japan. tsugiyama@poh.osaka-med.ac.jp

Telephone: +81-75-8014151 Fax: +81-75-8227423

Received: October 22, 2013
Revised: December 4, 2013
Accepted: January 6, 2014
Published online: April 15, 2014

Core Tip

Core tip: This review summarizes the studies regarding the putative role of the P2X₇ receptor in triggering purinergic vasotoxicity in the retina and thereby contributing to the progression of diabetic retinopathy.