Review
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World J Diabetes. Dec 15, 2013; 4(6): 238-244
Published online Dec 15, 2013. doi: 10.4239/wjd.v4.i6.238
Effect of obstructive sleep apnea on type 2 diabetes mellitus: A comprehensive literature review
Srikant Nannapaneni, Kannan Ramar, Salim Surani
Srikant Nannapaneni, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55902, United States
Kannan Ramar, Center for Sleep Medicine, Mayo Clinic, Rochester, MN 55905, United States
Salim Surani, Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Texas A and M University, Corpus Christi, TX 78413, United States
Author contributions: Nannapaneni S, Ramar K, and Surani S contributed equally to this document.
Correspondence to: Salim Surani, MD MD, MPH, MSHM, FACP, FCCP, FAASM, Associate Professor, Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Texas A and M University, 7613 Lake Bolsena, Corpus Christi, TX 78413, United States. srsurani@hotmail.com
Telephone: +1-361-8857722 Fax: +1-361-8507563
Received: June 17, 2013
Revised: November 5, 2013
Accepted: November 15, 2013
Published online: December 15, 2013
Core Tip

Core tip: This manuscript addresses the effect of obstructive sleep apnea (OSA) on type 2 diabetes (T2DM) and its associated vascular complications. Specifically, this article provides a comprehensive review of the association between OSA and the microvascular complications of T2DM. Finally, a summary of the effect of the use of continuous positive airway pressure treatment in individuals with OSA and T2DM is reviewed.