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World J Diabetes. Apr 15, 2013; 4(2): 19-26
Published online Apr 15, 2013. doi: 10.4239/wjd.v4.i2.19
Bevacizumab for the management of diabetic macular edema
Francisco Rosa Stefanini, J Fernando Arevalo, Maurício Maia
Francisco Rosa Stefanini, Maurício Maia, The Retina Division, Ophthalmology Department, Federal University of São Paulo, São Paulo, SP 04023-062, Brazil
J Fernando Arevalo, The Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States
J Fernando Arevalo, The King Khaled Eye Specialist Hospital, Riyadh 11462, Saudi Arabia
Maurício Maia, Brazilian Institute of Fighting Against Blindness, Assis/Presidente Prudente, São Paulo, SP 04023-062, Brazil
Author contributions: Stefanini FR reviewed the literature and wrote the first draft of the manuscript; Arevalo JF and Maia M contributed equally to the literature search and reviewed the draft and revised versions of the manuscript; all authors approved the final version of the manuscript to be published.
Correspondence to: Francisco Rosa Stefanini, MD, The Retina Division, Ophthalmology Department, Federal University of São Paulo, Rua Botucatu, 821, Vila Clementino, São Paulo, SP 04023-062, Brazil. franstefanini@yahoo.com.br
Telephone: +55-11-50852010 Fax: +55-11-50852000
Received: October 24, 2012
Revised: February 15, 2013
Accepted: March 23, 2013
Published online: April 15, 2013
Core Tip

Core tip: This review summarizes the studies examining bevacizumab for the management of diabetic macular edema (DME), focusing on the efficacy and duration of the clinical benefits of decreasing DME and the improvement of best-corrected visual acuity.