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World J Diabetes. Oct 15, 2026; 17(10): 122682
Published online Oct 15, 2026. doi: 10.4239/wjd.122682
Published online Oct 15, 2026. doi: 10.4239/wjd.122682
Post vitrectomy alterations of retinal microcirculation in complicated diabetic retinopathy with and without silicone oil
Yan-Hui Xiao, Wen-Peng Zhang, Zhen-Yu Wang, Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
Author contributions: Wang ZY designed the research and performed the surgery; Xiao YH and Zhang WP collected and analyzed the patient data; Xiao YH drafted the manuscript; Zhang WP prepared the tables and figures; all authors reviewed the final manuscript and approved the submitted version.
AI contribution statement: AI is solely employed for proofreading: Such as spelling, grammar, linguistic refinement and so on. The authors take full responsibility and accountability for all content of this manuscript, including any portions for which AI tools were used as assistive technologies. All AI-assisted outputs were carefully reviewed, validated, and approved by the authors. AI tools were not used to generate original scientific data, perform independent scientific analyses, or draw scientific conclusions.
Supported by National Natural Science Foundation of China, No. 81700796.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of the First Affiliated Hospital of Soochow University (2024 Review No. 357) and conducted in accordance with the tenets of the Declaration of Helsinki.
Informed consent statement: Written informed consent was obtained from all participants after detailed explanation of the study procedures and potential risks.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest related to this work.
Data sharing statement: The datasets used and analysed in this study are available from the corresponding author upon reasonable request. This article has no additional Supplementary materials.
Corresponding author: Zhen-Yu Wang, Department of Ophthalmology, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Street, Suzhou 215006, Jiangsu Province, China. llbtiao@suda.edu.cn
Received: April 30, 2026
Revised: June 15, 2026
Accepted: September 4, 2026
Published online: October 15, 2026
Processing time: 159 Days and 1.3 Hours
Revised: June 15, 2026
Accepted: September 4, 2026
Published online: October 15, 2026
Processing time: 159 Days and 1.3 Hours
Core Tip
Core Tip: This study explored changes of retinal microcirculation in patients with complicated diabetic retinopathy after silicone oil (SO) tamponade using optical coherence tomography angiography (OCTA). SO tamponade was associated with decreased deep retinal vascular density (VD), increased retinal thickness, and enlargement of the foveal avascular zone (FAZ). After SO removal, deep retinal VD partially increased, whereas FAZ enlargement persisted. OCTA may serve as a valuable tool for postoperative follow-up and clinical management of patients after vitrectomy.