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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jun 15, 2025; 16(6): 99602
Published online Jun 15, 2025. doi: 10.4239/wjd.v16.i6.99602
Published online Jun 15, 2025. doi: 10.4239/wjd.v16.i6.99602
Retroauricular subperiosteal vs systemic intravenous glucocorticoid administration on efficacy and blood glucose in diabetic patients with sudden deafness
Juan Long, Department of Otolaryngology-Head and Neck Surgery, Changsha Chang Hao Hospital, Changsha 201102, Hunan Province, China
Hong-Wei Zuo, Department of Otolaryngology, Head and Neck Surgery, Zibo Central Hospital, Zibo 255000, Shandong Province, China
Author contributions: Long J designed the research study; Long J and Zuo HW performed the research; Long J and Zuo HW analyzed the data and wrote the manuscript; All authors have read and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Zibo Central Hospital, No. 2024-134.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Wei Zuo, Department of Otolaryngology, Head and Neck Surgery, Zibo Central Hospital, No. 10 Shanghai Road, Zhangdian District, Zibo 255000, Shandong Province, China. 18765690762@163.com
Received: December 5, 2024
Revised: March 5, 2025
Accepted: April 9, 2025
Published online: June 15, 2025
Processing time: 190 Days and 2.9 Hours
Revised: March 5, 2025
Accepted: April 9, 2025
Published online: June 15, 2025
Processing time: 190 Days and 2.9 Hours
Core Tip
Core Tip: Managing sudden deafness in patients with diabetes poses significant therapeutic challenges, particularly due to the limitations of systemic drug administration, prompting the exploration of retroauricular subperiosteal methylprednisolone injection as a potentially superior clinical approach. Our comprehensive analysis revealed that retroauricular subperiosteal injection of methylprednisolone yields significantly better therapeutic outcomes compared with systemic intravenous infusion and demonstrates enhanced safety profiles and minimal impact on blood glucose levels. This finding underscores its potential as a safer and more effective treatment strategy, offering substantial clinical value and practical significance.