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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jul 15, 2022; 13(7): 543-552
Published online Jul 15, 2022. doi: 10.4239/wjd.v13.i7.543
Published online Jul 15, 2022. doi: 10.4239/wjd.v13.i7.543
Elevated levels of fructosamine are independently associated with SARS-CoV-2 reinfection: A 12-mo follow-up study
Xiao-Yan Huang, Li-Juan Yang, Xiang Hu, Xing-Xing Zhang, Xiao Gu, Lin-Jia Du, Zhi-Ying He, Xue-Jiang Gu, Department of Endocrine and Metabolic Disease, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Xiao-Yan Huang, Department of Endocrine and Metabolic Disease, Yueqing People’s Hospital, Affiliated Hospital of Wenzhou Medical University, Wenzhou 325600, Zhejiang Province, China
Author contributions: Gu XJ was the guarantor and designed the study; Huang XY and Hu X participated in the acquisition, analysis, interpretation of the data, and drafted the initial manuscript; Yang LY, Zhang XX, Gu X, Du LJ, and He ZY revised the article critically for important intellectual content.
Institutional review board statement: The study protocol was approved by the Ethics Committee of Yueqing People’s Hospital, Affiliated Hospital of Wenzhou Medical University (No. YQYY202100033).
Informed consent statement: The informed consent statement was waived.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Jiang Gu, MMed, Chief Doctor, Department of Endocrine and Metabolic Disease, The First Affiliated Hospital of Wenzhou Medical University, Shangcai Village, Nanbaixiang Street, Ouhai District, Wenzhou 325000, Zhejiang Province, China. guxuejiang@wmu.edu.cn
Received: December 8, 2021
Peer-review started: December 8, 2021
First decision: April 18, 2022
Revised: April 29, 2022
Accepted: June 13, 2022
Article in press: June 13, 2022
Published online: July 15, 2022
Peer-review started: December 8, 2021
First decision: April 18, 2022
Revised: April 29, 2022
Accepted: June 13, 2022
Article in press: June 13, 2022
Published online: July 15, 2022
Core Tip
Core Tip: Diabetes is a risk factor for coronavirus disease 2019 (COVID-19), which results in increased severity and mortality but has no relationship with reinfection. The present study, for the first time, reported the relationship between severe acute respiratory syndrome coronavirus 2 reinfection and blood levels of fructosamine (FMN), an index reflecting recent glycemic control. Our results demonstrated that FMN levels may influence the prognosis of patients with COVID-19, and patients with high FMN levels should be followed closely to monitor reinfection.