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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Dec 15, 2021; 12(12): 2000-2010
Published online Dec 15, 2021. doi: 10.4239/wjd.v12.i12.2000
Published online Dec 15, 2021. doi: 10.4239/wjd.v12.i12.2000
Progress and prospect of stem cell therapy for diabetic erectile dysfunction
Dao-Sheng Luo, Zhi-Quan Deng, Department of Urology, Dongguan People’s Hospital, Dongguan 523000, Guangdong Province, China
Yan-Qing Li, Gui-Hua Liu, Reproductive Centre, Sun Yat-Sen University, The Sixth Affiliated Hospital, Guangzhou 510000, Guangdong Province, China
Author contributions: Liu GH and Luo DS designed the research study; Luo DS and Li YQ performed the literature retrieval and analysis; Li YQ and Deng ZQ wrote the manuscript; All authors have read and approved the final manuscript.
Supported by the National Natural Science Foundation of China , No. 81971759 .
Conflict-of-interest statement: The authors declare that there are no conflicts of interest associated with this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guihua Liu, MD, PhD, Associate Chief Physician, Associate Research Scientist, Reproductive Centre, Sun Yat-Sen University, The Sixth Affiliated Hospital, No. 26 Yuancuner Rd., Tianhe District, Guangzhou 510000, Guangdong Province, China. liuguihua@mail.sysu.edu.cn
Received: February 6, 2021
Peer-review started: February 7, 2021
First decision: March 8, 2021
Revised: March 18, 2021
Accepted: October 31, 2021
Article in press: November 3, 2021
Published online: December 15, 2021
Peer-review started: February 7, 2021
First decision: March 8, 2021
Revised: March 18, 2021
Accepted: October 31, 2021
Article in press: November 3, 2021
Published online: December 15, 2021
Core Tip
Core Tip: Diabetic erectile dysfunction (DED) is a common complication of diabetes. Conventional clinical treatments like phosphodiesterase-5 inhibitors, intracavernosal vasoactive drug injection, negative pressure suction device, and low-intensity shock wave therapy are the conventional methods of clinical treatment. However, none of the above therapies has the potential of curing. Stem cell therapy is currently the only possible cure for DED and can avoid the potential complications of conventional therapies. Here we discuss the current role and progress of stem cells in the treatment of DED.