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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2020; 11(9): 391-399
Published online Sep 15, 2020. doi: 10.4239/wjd.v11.i9.391
Published online Sep 15, 2020. doi: 10.4239/wjd.v11.i9.391
Lower extremity amputations and long-term outcomes in diabetic foot ulcers: A systematic review
Ayeshmanthe Rathnayake, Apoorva Saboo, Usman H Malabu, Usman H Malabu, Department of Medicine, Townsville University Hospital, Townsville 4814, Queensland, Australia
Usman H Malabu, School of Medicine and Dentistry, James Cook University, Townsville 4811, Queensland, Australia
Henrik Falhammar, Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm 17176, Sweden
Henrik Falhammar, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden
Author contributions: Rathnayake A contributed to acquisition of data, analysis and interpretation of data, drafting the article; Saboo A contributed to acquisition of data, analysis and interpretation of data, drafting the article; Malabu U contributed to interpretation of data, revising the article, final approval; Falhammar H contributed to interpretation of data, revising the article, final approval.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ayeshmanthe Rathnayake, MBBS, Doctor, Department of Medicine, Townsville University Hospital, 100 Angus Smith Drive, Townsville 4817, Queensland, Australia. ayeshmantherathnayake@gmail.com
Received: May 7, 2020
Peer-review started: May 7, 2020
First decision: May 24, 2020
Revised: June 6, 2020
Accepted: August 15, 2020
Article in press: August 15, 2020
Published online: September 15, 2020
Peer-review started: May 7, 2020
First decision: May 24, 2020
Revised: June 6, 2020
Accepted: August 15, 2020
Article in press: August 15, 2020
Published online: September 15, 2020
Core Tip
Core Tip: There was a significantly higher degree of re-amputation and mortality in those who undergo amputations due to diabetic foot ulcers in addition to impact on quality of life. Data on long-term outcomes in these patients were limited and requires further research to better understand the long-term outcomes in this subset of patients.