Scientometrics
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2022; 13(9): 786-798
Published online Sep 15, 2022. doi: 10.4239/wjd.v13.i9.786
Mapping the global research landscape on insulin resistance: Visualization and bibliometric analysis
Sa’ed H Zyoud, Muna Shakhshir, Amer Koni, Amani S Abushanab, Moyad Shahwan, Ammar Abdulrahman Jairoun, Rand Al Subu, Adham Abu Taha, Samah W Al-Jabi
Sa’ed H Zyoud, Amer Koni, Amani S Abushanab, Samah W Al-Jabi, Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Sa’ed H Zyoud, Poison Control and Drug Information Center, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Sa’ed H Zyoud, Clinical Research Centre, An-Najah National University Hospital, Nablus 44839, Palestine
Muna Shakhshir, Department of Nutrition, An-Najah National University Hospital, Nablus 44839, Palestine
Amer Koni, Division of Clinical Pharmacy, Department of Hematology and Oncology Ph-armacy, An-Najah National University Hospital, Nablus 44839, Palestine
Moyad Shahwan, Department of Pharmacy, Ajman University, Ajman 346, United Arab Emirates
Moyad Shahwan, Centre of Medical and Bio Allied Health Sciences Research, Ajman University, Ajman 346, United Arab Emirates
Ammar Abdulrahman Jairoun, Department of Health and Safety, Dubai Municipality, Dubai 67, United Arab Emirates
Rand Al Subu, Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Adham Abu Taha, Department of Biomedical Sciences, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Adham Abu Taha, Department of Pathology, An-Najah National University Hospital, Nablus 44839, Palestine
Author contributions: Zyoud SH developed the concept for the manuscript, reviewed the literature, designed the study, collected the data, analyzed the data, made significant contributions to the existing literature search and interpretation of the manuscript, and wrote the manuscript; Shakhshir M, Koni A, Abushanab AS, Jairoun AA, Shahwan WM, Al Subu R, Abu Taha A, and Al-Jabi SW participated in interpretation of the data and made revisions to the initial draft; and all authors provided critical review and approved the final manuscript before submission.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sa’ed H Zyoud, PhD, Associate Professor, Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Academic Street, Nablus 44839, Palestine. saedzyoud@yahoo.com
Received: March 3, 2022
Peer-review started: March 3, 2022
First decision: April 17, 2022
Revised: May 4, 2022
Accepted: August 5, 2022
Article in press: August 5, 2022
Published online: September 15, 2022
ARTICLE HIGHLIGHTS
Research background

Insulin resistance is a condition in which muscle cells take up and store glucose and triglycerides, resulting in elevated amounts of glucose and triglycerides circulating in the bloodstream.

Research motivation

Several bibliometric studies have been carried out on the subject of diabetic investigation. However, no bibliometric study has been done on research into insulin resistance.

Research objectives

This bibliometric study aimed to identify and assess the current state and trends in insulin resistance research production worldwide and visually analyze research hotspots on this subject.

Research methods

The Scopus database and Reference Citation Analysis were used to compile the literature on insulin resistance. In addition, VOSviewer software was used to visually assess data collected from relevant publications.

Research results

This is the first bibliometric analysis of trends in insulin resistance. The number of publications on insulin resistance has increased in the last decade. Our results indicated that the “inflammatory mechanisms in the regulation of insulin resistance” and “mechanisms linking obesity to insulin resistance” will remain research hotspots in the future.

Research conclusions

Our findings indicate that interest in insulin resistance has gradually increased among researchers, as shown by the increasing number of citations and annual publications. Moreover, publications in this field have increased significantly in the last decade, while low-income countries with higher burdens continue to produce fewer publications.

Research perspectives

This paper contributes essential information by providing references and suggestions for future research on pathophysiology and clinical uses of insulin resistance. This approach may aid researchers in identifying new topics of inquiry and identifying research hotspots and frontiers. Perhaps in the future, high-quality clinical evidence will be collected.