Published online Mar 15, 2020. doi: 10.4239/wjd.v11.i3.78
Peer-review started: August 21, 2019
First decision: October 13, 2019
Revised: November 21, 2019
Accepted: January 8, 2020
Article in press: January 8, 2020
Published online: March 15, 2020
Globally, the occurrence of diabetic foot ulceration (DFU) reported as a significant health concern which calls for early prevention and diagnosis.
This study would assist in setting out relevant guidelines for reducing the incidence of DFU and overcome the resistance among patients for its treatment.
The main objectives were to examine the interrelationships between foot ulcers, risk factors, and antibiotic resistance among diabetic patients having ulcers in their foot.
A systematic and meta-analysis method is adopted for providing comprehensive insights on the DFU prevalence, risk factors as well as its resistance.
The research findings showed an increased prevalence of gram-negative bacteria among the DFU cases.
The review concludes hypertension and neuropathy as the major risk factors among DFU patients.
The review highlights that antimicrobial susceptibility can be considered for attaining better treatment outcomes.