Observational Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Feb 15, 2015; 6(1): 208-216
Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.208
Glycaemic control, treatment satisfaction and quality of life in type 2 diabetes patients in Greece: The PANORAMA study Greek results
Iraklis Avramopoulos, Alexandros Moulis, Nikos Nikas
Iraklis Avramopoulos, Hypertension Clinic, Hygeia Hospital, 15123 Maroussi, Athens, Greece
Alexandros Moulis, Nikos Nikas, Medical Department, AstraZeneca SA, 15125 Athens, Greece
Author contributions: All authors contributed to this manuscript.
Supported by AstraZeneca/Bristol-Myers Squibb.
Ethics approval: The study has been approved by the appropriate ethical committee of Hygeia hospital.
Informed consent: All authors are informed and agree with the context of the present manuscript.
Conflict-of-interest: Dr. Iraklis Avramopoulos has participated in lectures with AstraZeneca. Nikos Nikas and Alexandros Moulis are AstraZeneca employees.
Data sharing: Technical appendix, statistical code, and dataset available from the corresponding author at avramopoulos@medweb.gr. Consent from participants was not obtained but the presented data are anonymized and risk of identification is low.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Iraklis Avramopoulos, Hypertension Clinic, Hygeia Hospital, Er. Stavrou 4, 15123 Maroussi, Athens, Greece. avramopoulos@medweb.gr
Telephone: +30-21-06867060 Fax: +30-21-06867225
Received: September 9, 2014
Peer-review started: September 9, 2014
First decision: November 3, 2014
Revised: November 24, 2014
Accepted: December 16, 2014
Article in press: December 17, 2014
Published online: February 15, 2015

AIM: To provide an update on glycaemic control in European patients with type 2 diabetes mellitus (T2DM). We present the Greek population data of the study.

METHODS: An observational multicenter, cross-sectional study evaluating glycaemic control and a range of other clinical and biological measures as well as quality of life (QoL) and treatment satisfaction in 375 patients with T2DM enrolled by 25 primary care sites from Greece.

RESULTS: The mean age of the patients was 63.5 years and the male/female ratio 48.9%/51.1%. 79.7% of the patients exerted none or light physical activity, 82.4% were overweight or obese and 32.9% did not meet HbA1c target of less than 7.0% (53 mmol/mol). Patients reported high satisfaction to continue with treatment, high satisfaction with administered treatment and increased willingness to recommend treatment to others (mean Diabetes Treatment Satisfaction Questionnaire score 29.1 ± 5.6). However, 80% of the patients reported that their QoL would be better without diabetes. Finally, the most challenging parameter reported was the lack of freedom to eat and drink.

CONCLUSION: This analysis of the Greek Panorama study results showed that a considerable percentage of T2DM patients in Greece do not achieve glycaemic target levels, despite the favourably reported patient satisfaction from administered therapy. Additionally, the majority of primary care T2DM patients in Greece depict the negative effect of the disease in their QoL.

Keywords: Quality of life, Treatment satisfaction, Type 2 diabetes mellitus

Core tip: Diabetes is a common, chronic disease with serious complications. Despite the multiple antidiabetic treatment options and the clear treatment guidelines, a significant proportion of type 2 diabetes patients do not achieve the glycaemic goals. Few studies have examined the quality of life in these patients. PANORAMA was a Pan-European multinational study that provided an update of the glycaemic control and quality of life in patients with diabetes. The Greek results of this study showed that a significant proportion of Greek patients were not under glycaemic control despite the high satisfaction that they had from their treatment. A negative impact of the disease in quality of life was also noted.