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World J Diabetes. Apr 15, 2012; 3(4): 65-70
Published online Apr 15, 2012. doi: 10.4239/wjd.v3.i4.65
Published online Apr 15, 2012. doi: 10.4239/wjd.v3.i4.65
Effect of continuous positive airway pressure therapy on glucose control
Salim Surani, Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, TAMU, Corpus Christi, TX 78404, United States
Shyam Subramanian, Pulmonary, Division of Critical Care and Sleep Medicine, Department of Medicine, Case Western University, Cleveland, OH 44106, United States
Author contributions: Surani S and Subramanian S contributed equally to the work, including collection of data and preparation of the manuscript.
Correspondence to: Salim Surani, MD, Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, TAMU, 613 Elizabeth Street, Suite 813, Corpus Christi, TX 78404, United States. srsurani@hotmail.com
Telephone: +1-361-885-7722 Fax: +1-361-850-7563
Received: November 25, 2011
Revised: March 27, 2012
Accepted: April 10, 2012
Published online: April 15, 2012
Revised: March 27, 2012
Accepted: April 10, 2012
Published online: April 15, 2012
Abstract
Obstructive sleep apnea (OSA) and diabetes mellitus are both highly prevalent disorders. There has been a recent recognition of an association between insulin resistance and sleep apnea. Continuous positive airway pressure (CPAP) has emerged as an effective therapy for treatment of OSA and has been shown to positively influence numerous pathophysiological factors that contribute to cardiovascular risk. There is emerging data that explores the influence of CPAP therapy, insulin sensitivity and glycemic control. In the current review, we examine this literature critically and formulate a synopsis that summarizes the current knowledge in this field.
Keywords: Obstructive sleep apnea, Continuous positive airway pressure, Diabetes, Metabolic syndrome