Pancreatic cancer: A model cancer for the study of the therapeutic effects of anticoagulants

Table 1 Impact of VTE on survival in the NCI-CTG PA.3 study

Variable	HR	95% CI	P value
Treatment effect
Erlotinib	0.79	0.66-0.95	0.01
Placebo	1.0
Thrombosis effect
VTE	2.33	1.82-2.98	< 0.0001
No VTE	1.0
Performance status
ECOG 2+	1.69	1.35-2.12	< 0.0001
ECOG 0-1	1.0
Extent of disease
Local	0.60	0.48-0.74	< 0.0001
Distant	1.0

Reprinted with permission^© 2008 American Society of Clinical Oncology. All rights reserved. VTE: Vascular thromboembolic disease.