Double contrast-enhanced ultrasonography in an exophytic gastric glomus tumor with unremarkable gastroscopy: A case report

Figure 1 Imaging findings of the gastric glomus tumor. A and B: Contrast-enhanced computed tomography showed a well-defined enhancing nodule in the gastric antrum on axial and sagittal images (arrows; scale bar: 5 cm); C: Double contrast-enhanced ultrasonography demonstrated a hypoechoic ovoid lesion on the greater curvature of the gastric antrum, slightly protruding outward; D: Color Doppler ultrasonography revealed abundant intralesional blood flow signals (arrow; scale bar: 5 mm); E: Contrast-enhanced ultrasonography and the corresponding time–intensity curve demonstrated earlier and stronger enhancement of the lesion than the adjacent gastric wall, followed by slight washout while remaining hyperenhanced in the delayed phase.

Figure 2 Surgical and pathological findings of the gastric glomus tumor. A: Hematoxylin and eosin staining showed nests and sheets of relatively uniform round tumor cells arranged around dilated vascular channels (arrows; scale bar: 100 μm); B: Immunohistochemical staining demonstrated positive expression of smooth muscle actin in the tumor cells; C: Intraoperative laparoscopic view revealed a protruding mass on the gastric wall; D: Gross appearance of the resected specimen showed a well-circumscribed nodular lesion.