Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas

doi:10.4251/wjgo.v14.i11.2195

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Oncol. Nov 15, 2022; 14(11): 2195-2207
Published online Nov 15, 2022. doi: 10.4251/wjgo.v14.i11.2195

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Figure 1 DNA sequence mutation analysis. A and B: Overview of mutations detected in screen-detected colorectal cancer (CRC) (A) and in fecal immunochemical test-CRC (B). SD-CRC: Screen-detected colorectal cancer; FIT-CRC: Fecal immunochemical test- colorectal cancer.

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Figure 2 DNA copy number alterations in fecal immunochemical test-interval and screen-detected colorectal cancers, scale at 50%. A: Fecal immunochemical test-interval colorectal cancers (CRCs); B: Screen-detected CRCs. SD-CRC: Screen-detected colorectal cancer; FIT-CRC: Fecal immunochemical test- colorectal cancer.

Citation: van der Vlugt M, Carvalho B, Fliers J, Montazeri N, Rausch C, Grobbee EJ, Engeland MV, Spaander MCW, Meijer GA, Dekker E. Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas. World J Gastrointest Oncol 2022; 14(11): 2195-2207
URL: https://www.wjgnet.com/1948-5204/full/v14/i11/2195.htm
DOI: https://dx.doi.org/10.4251/wjgo.v14.i11.2195