Clinical characteristics and outcome of primary hepatic neuroendocrine tumors after comprehensive therapy

Figure 1 Survival analysis showed that tumor grade, AE1/AE3, and Ki-67 were significantly related to the overall survival rate.

Figure 2 There are multiple low-density lesions in the liver with nonuniform radioactive distribution. A and B: The size of the largest lesion is 2.3 cm × 2.8 cm, and the computed tomography value is 36 HU; C and D: Smaller lesion.

Figure 3 Comparison of computed tomography images of the liver lesion before and after long-acting repeatable octreotide treatment. A and B: Pre-treatment images; C and D: Post-treatment images.

Figure 4 Hematoxylin-eosin staining indicated the possibility of cancer, and further immunohistochemistry was performed. The tumor was regarded as a highly differentiated neuroendocrine tumor according to the results. The tumor was positive for Syn, AE1/AE3, CD34, CK7, CK8, CD56, and CK19 (magnification, 200 ×).

Figure 5 Positron emission tomography-computed tomography was carried out after surgery and showed that the margin of the low-density shadow in the right hepatic lobe was more active and more likely attributable to postoperative changes. No other obvious abnormalities were observed.