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World J Gastrointest Oncol. Mar 15, 2016; 8(3): 289-296
Published online Mar 15, 2016. doi: 10.4251/wjgo.v8.i3.289
Role of genetic detection in peritoneal washes with gastric carcinoma: The past, present and future
Hyun-Dong Chae
Hyun-Dong Chae, Department of Surgery, School of Medicine, Catholic University of Daegu, Daegu 705-718, South Korea
Author contributions: The author solely contributed to this paper.
Conflict-of-interest statement: I have no conflict of interest to disclose and received no funding from the manufacturer of any drug, treatment, or appliance in the performance of this study and I have no other potential conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hyun-Dong Chae, MD, PhD, Department of Surgery, School of Medicine, Catholic University of Daegu, 3056-6, Daemyung-4-Dong, Namgu, Daegu 705-718, South Korea. hdchae@cu.ac.kr
Telephone: +82-53-6504429 Fax: +82-53-6247185
Received: June 26, 2015
Peer-review started: June 27, 2015
First decision: July 28, 2015
Revised: October 25, 2015
Accepted: December 17, 2015
Article in press: December 18, 2015
Published online: March 15, 2016
Processing time: 254 Days and 23.2 Hours
Core Tip

Core tip: The most common cause of treatment failure after gastric cancer surgery is peritoneal metastasis, mainly caused by free cancer cells from primary cancer. Genetic detection using reverse transcriptase polymerase chain reaction analysis has been used for the detection of free cancer cells. The process and method of genetic detection with peritoneal washes should be standardized, and the development of simple diagnostic devices and easily available kits are necessary in the future. In this article, we summarize the current evidence of genetic detection in peritoneal washes from gastric cancer patient.