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World J Gastrointest Oncol. Jun 15, 2014; 6(6): 156-169
Published online Jun 15, 2014. doi: 10.4251/wjgo.v6.i6.156
Published online Jun 15, 2014. doi: 10.4251/wjgo.v6.i6.156
Primary tumor resection in colorectal cancer with unresectable synchronous metastases: A review
Louis de Mestier, Olivier Bouché, Department of Gastroenterology and Digestive Oncology, Robert-Debré University Hospital, 51100 Reims, France
Gilles Manceau, Jean Christophe Vaillant, Laurent Hannoun, Mehdi Karoui, Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Department of Digestive and Hepato-Pancreato-Biliary Surgery, University Institute of Cancerology (Paris VI), Pierre and Marie Curie University, 75013 Paris, France
Cindy Neuzillet, Assistance Publique-Hôpitaux de Paris, Department of Gastroenterology and Pancreatology, Beaujon University Hospital, 92110 Clichy, France
Jean Baptiste Bachet, Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Department of Gastroenterology, University Institute of Cancerology (Paris VI), Pierre and Marie Curie University, 75013 Paris, France
Jean Philippe Spano, Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Department of Medical Oncology, University Institute of Cancerology (Paris VI), Pierre and Marie Curie University, 75013 Paris, France
Reza Kianmanesh, Department of Digestive and Endocrine Surgery, Robert-Debré University Hospital, 51100 Reims, France
Author contributions: de Mestier L, Manceau G, Neuzillet C, Bachet JB, Spano JP, Kianmanesh R, Vaillant JC, Bouché O, Hannoun L and Karoui M designed research; de Mestier L, Manceau G, Karoui M performed research; de Mestier L, Manceau G and Karoui M analyzed data; de Mestier L, Manceau G, Neuzillet C, Bachet JB, Spano JP, Kianmanesh R, Vaillant JC, Bouché O, Hannoun L and Karoui M wrote the paper.
Correspondence to: Mehdi Karoui, MD, PhD, Professor of Surgery, Assistance Publique-Hôpitaux de Paris, Pitié Salpêtrière University Hospital, Department of Digestive and Hepato-Pancreato-Biliary Surgery, University Institute of Cancerology (Paris VI), Pierre and Marie Curie University, 47-83 Boulevard de l’Hôpital, 75013 Paris, France. mehdi.karoui@psl.aphp.fr
Telephone: +33-1-42175612 Fax: +33-1-42175613
Received: November 17, 2013
Revised: April 8, 2014
Accepted: May 13, 2014
Published online: June 15, 2014
Revised: April 8, 2014
Accepted: May 13, 2014
Published online: June 15, 2014
Core Tip
Core tip: The present review aimed to analyze all published data on whether primary tumor resection should be performed before chemotherapy administration in patients with colorectal cancer and unresectable synchronous metastases.