Review
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2025; 17(6): 105690
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105690
Progress of traditional Chinese medicine in the prevention and treatment of colorectal cancer
Li Mo, Yuan Wang, Xin-Yue Liang, Tao Zou, Yan Chen, Jin-Yu Tan, Jie Wen, Xiao-Hong Jian
Li Mo, Yuan Wang, Xin-Yue Liang, Tao Zou, Jin-Yu Tan, Department of Proctology, The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha 410010, Hunan Province, China
Yan Chen, Changsha Medical University, Changsha 410219, Hunan Province, China
Jie Wen, Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410013, Hunan Province, China
Xiao-Hong Jian, Department of Anatomy, Hunan Normal University School of Medicine, Changsha 410005, Hunan Province, China
Co-first authors: Li Mo and Yuan Wang.
Co-corresponding authors: Jin-Yu Tan and Jie Wen.
Author contributions: Mo L and Wang Y contributed equally to this study, they share co-first authors. Mo L and Wang Y wrote the paper; Liang XY and Zou T performed data collection; Chen Y performed the literature search; Wen J analyzed data; Tan JY and Jian XH revised the paper; Tan JY and Wen J contributed equally to this study, they share co-corresponding authors. All authors reviewed the results and approved the final version of the manuscript.
Supported by Hunan Provincial Natural Science Foundation, No. 2025JJ90028; and Changsha Natural Science Foundation Project, No. kq2502190.
Conflict-of-interest statement: The authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Wen, Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, No. 61 Jiefang West Road, Changsha 410013, Hunan Province, China. cashwj@qq.com
Received: February 4, 2025
Revised: March 7, 2025
Accepted: April 17, 2025
Published online: June 15, 2025
Processing time: 130 Days and 5.7 Hours
Core Tip

Core Tip: Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide, ranking high in both incidence and mortality rates. With a history spanning thousands of years, traditional Chinese medicine has shown unique efficacy and advantages in CRC prevention and treatment, playing a crucial role across all levels of China’s healthcare system. This article offers a comprehensive analysis and summary of traditional Chinese medicine’s contributions to CRC prevention, antitumor therapy, palliative care for advanced tumors, perioperative rehabilitation, and postoperative functional recovery.