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World J Gastrointest Oncol. Jun 15, 2025; 17(6): 104015
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.104015
Minimally invasive lymphadenectomy for gastric cancer: Could the robotic approach provide any benefits than laparoscopy?
Daniele Marrelli, Ludovico Carbone, Gianmario Edoardo Poto, Daniele Fusario, Mattheus Gjoka, Eleonora Andreucci, Stefania Angela Piccioni, Natale Calomino, Marta Sandini, Franco Roviello
Daniele Marrelli, Ludovico Carbone, Gianmario Edoardo Poto, Daniele Fusario, Mattheus Gjoka, Eleonora Andreucci, Stefania Angela Piccioni, Marta Sandini, Franco Roviello, Department of Medicine Surgery and Neuroscience, University of Siena, Siena 53100, Tuscany, Italy
Daniele Marrelli, Stefania Angela Piccioni, Natale Calomino, Franco Roviello, Department of Oncology, Azienda Ospedaliera Universitaria Senese, Siena 53100, Tuscany, Italy
Author contributions: Marrelli D, Carbone L, Poto GE, Fusario D, Gjoka M, Andreucci E, Piccioni SA, Calomino N, Sandini M, and Roviello F contributed to the study conception, and design; Marrelli D, Carbone L, and Poto GE contributed to the material preparation and data collection; Marrelli D, Carbone L, and Fusario D wrote the first draft of the manuscript; Gjoka M designed the figure; All authors provided comments on previous versions of the manuscript and read and approved the final manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Daniele Marrelli, MD, Professor, Department of Medicine Surgery and Neuroscience, University of Siena, Via Banchi di Sotto 55, Siena 53100, Tuscany, Italy. daniele.marrelli@ao-siena.toscana.it
Received: December 9, 2024
Revised: March 19, 2025
Accepted: March 20, 2025
Published online: June 15, 2025
Processing time: 188 Days and 13.8 Hours
Core Tip

Core Tip: Robotic gastrectomy is likely to become the way forward for treating gastric cancer. It offers technical advantages in terms of lower rate of intraoperative blood loss and postoperative complications, with comparable survival and lymph node retrieval to open surgery. Our systematic review of randomized control trials analyzes the potential benefits of robotic systems, sheds light on the remaining uncertainties, and outlines future lines of research. Further evidence is needed to confirm its advantages in postneoadjuvant cases.