Retrospective Cohort Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Mar 15, 2024; 16(3): 750-760
Published online Mar 15, 2024. doi: 10.4251/wjgo.v16.i3.750
Mucosa color and size may indicate malignant transformation of chicken skin mucosa-positive colorectal neoplastic polyps
Ying-Jie Zhang, Meng-Xia Yuan, Wu Wen, Fan Li, Yi Jian, Chuan-Ming Zhang, Ye Yang, Feng-Lin Chen
Ying-Jie Zhang, Meng-Xia Yuan, Wu Wen, Fan Li, Yi Jian, Chuan-Ming Zhang, Department of Digestive Diseases, Chengdu Second People’s Hospital, Chengdu 610000, Sichuan Province, China
Ye Yang, Feng-Lin Chen, Graduate School, Chengdu Medical College, Chengdu 610000, Sichuan Province, China
Author contributions: All authors contributed to the study conception and design; material preparation, Zhang YJ, Wen W, Li F, and Yuan MX performed data curation, and formal analysis; Zhang YJ, Jian Y, Zhang CM, and Yuan MX performed project administration and supervision; Zhang YJ wrote the original draft; Yuan MX, Yang Y, and Chen FL contributed to review and editing; All authors commented on subsequent versions of the manuscript, and all authors read and approved the final manuscript.
Supported by the Science and Technology Plan Project of Chengdu Municipal Health Commission, No. 2019007.
Institutional review board statement: This study was approved by the Ethics Committee of Chengdu Second People's Hospital, No. 2021018.
Informed consent statement: The requirement for informed consent was waived because our study does not invade personal privacy and has little risk to patients.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Meng-Xia Yuan, MD, Doctor, Department of Digestive Diseases, Chengdu Second People’s Hospital, No. 10 Qingyun South Street, Chengdu 610000, Sichuan Province, China. 1062274198@qq.com
Received: October 26, 2023
Peer-review started: October 26, 2023
First decision: December 5, 2023
Revised: January 2, 2024
Accepted: February 6, 2024
Article in press: February 6, 2024
Published online: March 15, 2024
Core Tip

Core tip: Chicken skin mucosa (CSM) has emerged as a critical feature of early colorectal cancer or pre-cancerous lesions. We performed further risk stratification analysis of CSM-positive colorectal polyps under white light endoscopy. Possible risk factors of malignant transformation and submucosal infiltration of CSM-positive colorectal polyps were proposed. Cold snare polypectomy was determined to be inadequate. CSM type was not associated with malignant transformation of neoplastic polyps or early submucosal invasion. We also confirmed that partial or complete resection of the CSM around colorectal adenomas did not affect tumor recurrence. The CSM disappeared within 12 months after polypectomy.