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World J Gastrointest Oncol. Feb 15, 2024; 16(2): 287-299
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.287
Targeting oxidative stress with natural products: A novel strategy for esophageal cancer therapy
Fang Cao, Han-Ling Zhang, Cui Guo, Xue-Liang Xu, Qiang Yuan
Fang Cao, Xue-Liang Xu, Qiang Yuan, Department of Rehabilitation III, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China
Han-Ling Zhang, Department of Rehabilitation, Chongqing Fuling District Maternal and Child Health Hospital, Chongqing 408000, China
Cui Guo, Department of Rehabilitation, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province, China
Co-first authors: Fang Cao and Han-Ling Zhang.
Co-corresponding authors: Xue-Liang Xu and Qiang Yuan.
Author contributions: Cao F and Zhang HL jointly wrote the paper; Cao F and Guo C collected and reviewed the literature and made charts; Cao F and Zhang HL coordinated and jointly wrote and revised the paper; Xu XL and Yuan Q conceived the review and put forward core opinions and suggestions; Cao F and Zhang HL contributed equally substantial efforts throughout the entire research process. Because this study was conducted through collaboration, the entire research team included authors with various professional knowledge and skills from different fields. The designation of co-first authors accurately reflects the distribution of responsibilities and burdens related to the time and effort required to complete the research and synthesize the paper. Meanwhile, the designation of co-corresponding authors ensures the accuracy and professionalism of the article. All authors have read and approved the manuscript.
Conflict-of-interest statement: All authors declare no potential conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Liang Xu, PhD, Doctor, Department of Rehabilitation III, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shierqiao Road, Chengdu 610072, Sichuan Province, China. 13408507171@163.com
Received: October 9, 2023
Peer-review started: October 9, 2023
First decision: December 5, 2023
Revised: December 12, 2023
Accepted: January 12, 2024
Article in press: January 12, 2024
Published online: February 15, 2024
Core Tip

Core Tip: This paper reviews the role of oxidative stress in esophageal cancer (ESC) development. Natural products (NPs) have shown beneficial effects throughout ESC disease processes. This review reveals the potential mechanisms by which NPs regulate ESC development through oxidative stress pathway.