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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Sep 15, 2020; 12(9): 1014-1030
Published online Sep 15, 2020. doi: 10.4251/wjgo.v12.i9.1014
Published online Sep 15, 2020. doi: 10.4251/wjgo.v12.i9.1014
γ-glutamyl transferase-to-platelet ratio based nomogram predicting overall survival of gallbladder carcinoma
Le-Jia Sun, Bao Jin, Gang Xu, Fei-Hu Xie, Hai-Feng Xu, Shun-Da Du, Yi-Yao Xu, Hai-Tao Zhao, Xin Lu, Xin-Ting Sang, Hua-Yu Yang, Yi-Lei Mao, Department of Liver Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
Ai Guan, Mei-Xi Liu, Huan-Huan Yin, Department of Clinical Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
Wei-Yu Xu, Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100730, China
Author contributions: Sun LJ, Guan A, and Xu WY contributed equally to this work; Sun LJ, Guan A, Xu WY, and Mao YL designed and coordinated the study; Yin HH, Liu MX, Jin B, Xu G, Xie FH, Xu HF, Du SD, Xu YY, Zhao HT, Lu X, Sang XT, and Yang HY performed the experiments; Guan A and Mao YL acquired and analyzed the data; Sun LJ and Guan A contributed to writing the original draft.
Supported by CAMS Innovation Fund for Medical Sciences , No. 2016-I2M-1-001 ; and Tsinghua University-Peking Union Medical College Hospital Cooperation Project , No. PTQH201904552 .
Institutional review board statement: All procedures were approved by the Medical Ethics Committee of Peking Union Medical College Hospital of the Chinese Academy of Medical Sciences and Peking Union Medical College and were conducted in accordance with the Helsinki Declaration of 1965 and later versions.
Informed consent statement: The requirement for informed consent was waived because of the retrospective nature of this study.
Conflict-of-interest statement: All the authors have declared no conflicts of interest related to this manuscript.
Data sharing statement: The data that support the findings of this study are available from the corresponding author upon reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yi-Lei Mao, MD, PhD, Doctor, Professor, Department of Liver Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuaifu Street, Beijing 100730, China. pumch-liver@hotmail.com
Received: May 2, 2020
Peer-review started: May 2, 2020
First decision: May 26, 2020
Revised: May 30, 2020
Accepted: August 4, 2020
Article in press: August 4, 2020
Published online: September 15, 2020
Peer-review started: May 2, 2020
First decision: May 26, 2020
Revised: May 30, 2020
Accepted: August 4, 2020
Article in press: August 4, 2020
Published online: September 15, 2020
Core Tip
Core Tip: We assessed the prognostic value of gamma-glutamyl transferase-to-platelet ratio (GPR) and designed a prognostic nomogram for gallbladder carcinoma (GBC). We retrospectively evaluated a group of 130 patients with GBC who underwent resection with either a high or low level of GPR. We proposed that GPR is an independent predictor of GBC prognosis, and nomogram-integrated GPR is a promising predictive model for overall survival in GBC patients.