Intraoperative intraperitoneal chemotherapy increases the incidence of anastomotic leakage after anterior resection of rectal tumors
Zhi-Jie Wang, Jin-Hua Tao, Jia-Nan Chen, Shi-Wen Mei, Hai-Yu Shen, Fu-Qiang Zhao, Qian Liu, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union College, Beijing 100021, China
Author contributions: Wang ZJ and Tao JH designed the research; Chen JN, Mei SW, Shen HY, and Zhao FQ collected and analyzed the data; Wang ZJ drafted the article; Liu Q revised the paper.
Supported by Medicine and Health Technology Innovation Project of Chinese Academy of Medical Sciences, No. 2017-12M-1-006.
Institutional review board statement: Our investigation received approval from the ethics committee of the National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union College.
Informed consent statement: All patients have signed an informed consent form before the study.
Conflict-of-interest statement: The authors declare that there is no conflict of interest in regard to this research.
STROBE statement: The authors have carefully read the STROBE Statement checklist of items and prepared the manuscript based on the requirements of STROBE Statement checklist of items.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Qian Liu, MD, Professor, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. firstname.lastname@example.org
Telephone: +86-10-87787110 Fax: +86-10-87787110
Received: January 27, 2019
Peer-review started: January 28, 2019
First decision: April 15, 2019
Revised: May 1, 2019
Accepted: May 28, 2019
Article in press: May 29, 2019
Published online: July 15, 2019