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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. May 15, 2019; 11(5): 416-423
Published online May 15, 2019. doi: 10.4251/wjgo.v11.i5.416
Published online May 15, 2019. doi: 10.4251/wjgo.v11.i5.416
Surgical resection of gastric stump cancer following proximal gastrectomy for adenocarcinoma of the esophagogastric junction
Fu-Hai Ma, Ying-Tai Chen, Wei-Kun Li, Yang Li, Wen-Zhe Kang, Yi-Bin Xie, Yu-Xin Zhong, Quan Xu, Yan-Tao Tian, Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Li-Yan Xue, Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Author contributions: Tian YT and Xue LY designed the research; Ma FH, Li WK and Chen YT analyzed the data and wrote the paper; Li Y, Kang WZ, Xie YB, Zhong YX and Xu Q collected the patient’s clinical data.
Supported by National Natural Science Foundation of China , No. 81772642 ; Beijing Municipal Science and Technology Commission , No. Z161100000116045 ; and Capital’s Funds for Health Improvement and Research, CFH 2018-2-4022 .
Institutional review board statement: This study was approved by the Institutional Review Board of the National Cancer Center Hospital.
Informed consent statement: The need for informed consent was waived due to the retrospective nature of the study, and the data were anonymously analyzed.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yan-Tao Tian, MD, Professor, Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Beijing 100021, China. tyt67@163.com
Telephone: +86-10-87787120 Fax: +86-10-87787120
Received: January 23, 2019
Peer-review started: January 23, 2019
First decision: March 14, 2019
Revised: April 1, 2019
Accepted: April 19, 2019
Article in press: April 19, 2019
Published online: May 15, 2019
Peer-review started: January 23, 2019
First decision: March 14, 2019
Revised: April 1, 2019
Accepted: April 19, 2019
Article in press: April 19, 2019
Published online: May 15, 2019
Core Tip
Core tip: The clinicopathological characteristics, treatment, and prognosis of gastric stump cancer (GSC) after distal gastrectomy have been well investigated, however, there is limited information on GSC after proximal gastrectomy (PG). We revealed characteristics of GSC in detail using the largest number of patients to date. Our results suggest that surgical approaches can achieve satisfactory outcomes in GSC following PG. The factor associated with OS based on multivariate analysis was advanced T stage and GSC is more likely to be diagnosed at an advanced stage. Thus, endoscopic follow-up of the gastric stump should be conducted to detect GSC at an early stage.