Published online May 15, 2019. doi: 10.4251/wjgo.v11.i5.348
Peer-review started: February 26, 2019
First decision: March 15, 2019
Revised: April 15, 2019
Accepted: May 3, 2019
Article in press: May 3, 2019
Published online: May 15, 2019
Core tip: This review aimed to investigate the effects of physical activity and the biological basis of these effects in preventing the risk and recurrence of colorectal cancer (CRC) and decreasing the hazards of cancer and cancer treatment. Several observational studies have demonstrated the efficacy and dose-dependent and anti-cancer effects of exercise on decreasing the mortality and risk of recurrence before and after the CRC diagnosis. However, the required exercise dose, type and intensity are yet unclear. The results of randomised prospective studies are expected.