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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Mar 15, 2019; 11(3): 250-263
Published online Mar 15, 2019. doi: 10.4251/wjgo.v11.i3.250
Published online Mar 15, 2019. doi: 10.4251/wjgo.v11.i3.250
Near-infrared fluorescence guided esophageal reconstructive surgery: A systematic review
Elke Van Daele, Yves Van Nieuwenhove, Wim Ceelen, Oswald Varin, Dirk Van de Putte, Wouter Willaert, Piet Pattyn, Department of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium
Christian Vanhove, Department of Electronics and information systems, Ghent University, Ghent B-9000, Belgium
Bart P Braeckman, Department of Biology, Ghent University, Ghent B-9000, Belgium
Anne Hoorens, Department of Pathology, Ghent University Hospital/Ghent University, Ghent B-9000, Belgium
Jurgen Van Limmen, Department of Anaesthesiology, Ghent University Hospital/ Ghent University, Ghent B-9000, Belgium
Author contributions: Van Daele E, Pattyn P, Van Nieuwenhove Y and Ceelen W designed the research; Van Daele E and Pattyn P performed the research and analysed the data; Van Daele E, Van Nieuwenhove Y and Ceelen W wrote the paper; Van Daele E and Ceelen W performed the statistical analysis; Vanhove C, Braeckman BP, Hoorens A, Van Limmen J, Varin O, Willaert W and Van de Putte D contributed to the manuscript reviewing and editing;
Supported by “ Kom op tegen Kanker” (Stand up to Cancer), the Flemish cancer society which has no role in the design of the study, nor in the collection, analysis or interpretation of the data or in the manuscripts’ writing .
Conflict-of-interest statement: The authors declare no conflicting interests related to this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Elke Van Daele, MD, Surgeon, Department of Gastrointestinal Surgery, Ghent University Hospital/Ghent University, University Hospital 2K12 IC, C. Heymanslaan 10, Ghent B-9000, Belgium. elke.vandaele@uzgent.be
Telephone: +32-9-3320829 Fax: +32-9-3323891
Received: November 27, 2018
Peer-review started: November 27, 2018
First decision: January 4, 2019
Revised: January 21, 2019
Accepted: January 29, 2019
Article in press: January 30, 2019
Published online: March 15, 2019
Peer-review started: November 27, 2018
First decision: January 4, 2019
Revised: January 21, 2019
Accepted: January 29, 2019
Article in press: January 30, 2019
Published online: March 15, 2019
Core Tip
Core tip: Esophagectomy is a surgery known for its complexity and potentially high morbidity associated with postoperative anastomotic leakage (AL). This review evaluates Indocyanine green fluorescence angiography (ICGA) as a safe, feasible and promising method to assess graft perfusion during esophageal reconstructive surgery. We discuss the safety, the methodology and the effectiveness of ICGA and its potential to reduce AL rate.