Observational Study
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Dec 15, 2019; 11(12): 1206-1217
Published online Dec 15, 2019. doi: 10.4251/wjgo.v11.i12.1206
Analysis of factors potentially predicting prognosis of colorectal cancer
Li-Jun Jin, Wei-Bin Chen, Xiao-Yu Zhang, Jie Bai, Hao-Chen Zhao, Zun-Yi Wang
Li-Jun Jin, Xiao-Yu Zhang, Jie Bai, Zun-Yi Wang, Department of Surgical Oncology (Division III), Cangzhou Central Hospital, Cangzhou 061001, Hebei Province, China
Wei-Bin Chen, Department of Radiology, North China University of Science and Technology Affiliated Hospital, Tangshan 063000, Hebei Province, China
Hao-Chen Zhao, Department of Anesthesiology (Division II), Cangzhou Central Hospital, Cangzhou 061001, Hebei Province, China
Author contributions: Jin LJ, Chen WB, Zhang XY, Bai J, Bai J, and Wang ZY designed the research; Jin LJ, Zhang XY, Bai J, and Wang ZY performed the research; Chen WB and Zhao HC contributed new analytic tools; Jin LJ, Zhao HC, and Wang ZY analyzed the data; and Jin LJ, Chen WB, Zhao HC, and Wang ZY wrote the paper.
Institutional review board statement: The study was approved by the Ethics Committee of Cangzhou Central Hospital.
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: There are no conflicts of interest to report.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zun-Yi Wang, MD, Doctor, Department of Surgical Oncology (Division III), Cangzhou Central Hospital, No. 16, Xinhua Road West, Cangzhou 061001, Hebei Province, China. czwzy99@163.com
Telephone: +86-317-2075979
Received: June 12, 2019
Peer-review started: June 18, 2019
First decision: July 31, 2019
Revised: August 5, 2019
Accepted: August 26, 2019
Article in press: August 26, 2019
Published online: December 15, 2019
Core Tip

Core tip: Accurate assessment of the prognosis after colorectal cancer surgery is of great importance in patients with colorectal cancer. This study systematically analyzed the influence of clinical data and serological and histological indicators on the prognosis of patients with colorectal cancer and the results revealed that the independent influence factors for the prognosis of colorectal cancer include tumor-node-metastasis stage, proliferating cell nuclear antigen, Glasgow prognostic score, neutrophil-lymphocyte ratio, C-reactive protein/albumin ratio, D-dimer, and carcinoembryonic antigen. The combined assessment of the independent factors is the most accurate predictor of the prognosis after colorectal cancer surgery.